S-Nitrosoglutathione-CAS 57564-91-7-Calbiochem

C₁₀H₁₆N₄O₇S

336.32

MFCD00214341

A utility carrier of nitric oxide. Breaks down at physiological pH to produce nitric oxide. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.
A utility carrier of nitric oxide. Breaks down to produce nitric oxide and a glutathione radical at pH 7.4. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

Product does not compete with ATP.
Primary Target
A utility carrier of nitric oxide
Reversible: no
Cell permeable: no

Toxicity: Standard Handling (A)

Reconstitute in cold distilled H₂O (4°C) free of divalent cations other than Ca²⁺.
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C or for up to 2 h at 4°C.

Sandau, K., et al. 1996. Cell Signal.8, 173.
Askew, S.C. 1995. Bioorg. Med. Chem.3, 1.
Fehsel, K., et al. 1995. J. Immunol.155, 2858.
de Belder, A.J., et al. 1994. Cardiovasc. Res.28, 691.
Sexton, D.J., et al. 1994. Photochem. Photobiol.59, 463.
Singh, R.J., et al. 1994. FEBS Lett. 360, 47.
Merryman, P.F., et al. 1993. Arthritis Rheum.36, 1414.
Park, J.W., et al. 1993. Biochem. Mol. Biol. Int.30, 885.
Radomski, M.W., et al. 1992. Br. J. Pharmacol.107, 745.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥95% (HPLC)

solid

Calbiochem^®

OK to freeze
desiccated (hygroscopic)
protect from light

pink

water: 10 mg/mL

ambient

−20℃

1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1

HYHSBSXUHZOYLX-WDSKDSINSA-N

50 mg in Plastic ampoule
10 mg in Glass bottle
1 set in Glass bottle
Packaged under inert gas

11 - Combustible Solids

WGK 3