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Cinoxacin
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4076285 | 1 G | 1142 | |||
| 4076285 | 5 G | 3650 |
产品别名
28657-80-9
Cinoxacin
1-Ethyl-1,4-dihydro-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H10N2O5 |
| Molecular weight | 262.22 |
| EC number【EC 号】 | 249-133-8 |
| MDL number | MFCD00056776 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278343 |
| NACRES | NA.85 |
| General description【一般描述】 | Chemical structure: quinolone |
| Application【应用】 | Cinoxacin was used to study the rat renal organic anion transporter 1 (OAT1). It is used to study fluoroquinolone-resistant Streptococcus pyogenes. |
| Biochem/physiol Actions【生化/生理作用】 | Cinoxacin is a synthetic antimicrobial agent that interferes with DNA replication by inhibiting DNA gyrase and topoisomerase IV (topo IV) through tight DNA binding. The mechanism of action of cinoxacin is comparable to nalidixic acid. Cinoxacin is effective against Gram-negative bacteria and is often used to treat urinary tract infections caused by E. coli, Proteus mirabilis, Proteus vulgaris and Klebsiella sp. |
| Other Notes【其他说明】 | Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C8645.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. Keep container tightly closed in a dry and well-ventilated place. |
产品性质
| Quality Level【质量水平】 | 200 |
| form【形式】 | powder or crystals |
| Mode of action【作用机制】 | DNA synthesis | interferes enzyme | inhibits |
| antibiotic activity spectrum【抗生素抗菌谱】 | Gram-negative bacteria |
| SMILES string | CCN1N=C(C(O)=O)C(=O)c2cc3OCOc3cc12 |
| InChI | 1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17) |
| InChI key | VDUWPHTZYNWKRN-UHFFFAOYSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
