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M871 trifluoroacetate
产品别名
M871 trifluoroacetate
WTLNSAGYLLGPEHPPPALALA-NH2, TFA salt
M 871, TFA salt
Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide, TFA salt
M-871, TFA salt
Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Glu-His-Pro-Pro-Pro-Ala-Leu-Alal-Leu-Ala-NH2, TFA salt
基本信息
| Empirical Formula【经验(实验)分子式】 | C108H163N27O28 · xC2HF3O2 |
| Molecular weight | 2287.61 (free base basis) |
| Biochem/physiol Actions【生化/生理作用】 | M871 is a type 2-selective galanin receptor antagonist (GalR2/GalR1 Ki = 13.1/410 nM by competitive binding against 0.1 nM porcine galanin using membranes from CHO expressing respective human receptors; GalR2/GalR1 Ki = 2.5/1.1 nM in case of rat galanin) that potently blocks 10 nM rat galanin-induced inositol phosphate production in human GalR2-expressing CHO cells (by 100% with 0.1, 1 or 10 nM M871). M871 is widely employed in cultures (0.1 nM-2.5 μM) and in mice and rats in vivo via ip., brain region- or other site-specific injections. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | lyophilized powder |
| color【颜色】 | white to off-white |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
