脱氧胆酸钠

C₂₄H₃₉NaO₄

414.55

3581950

MFCD00064139

An ionic detergent for the solubilization of membrane-bound proteins (aggregation number: 4-10; CMC: 4-8 mM; micellar weight: 1700-4200; pKa 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).
An ionic detergent for the solubilization of membrane-bound proteins. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 4-10.

Toxicity: Harmful (C)

Pai, R., et al. 2004. Mol. Biol. Cell15 2156.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥96% (TLC)

powder

micellar avg mol wt 1200-5000
micellar wt 1700-4200

Calbiochem^®

OK to freeze
desiccated (hygroscopic)

3-12
4 - 10

white to off-white

6.2

2-6 mM (20-25℃)
4 - 8 mM

H₂O: 2%, clear, colorless

heavy metals: ≤20.0 ppm

16

ambient

15-25℃

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

FHHPUSMSKHSNKW-SMOYURAASA-M

1 kg in Glass bottle
25, 100 g in Glass bottle

GHS07

Warning

H302 - H412

P264 - P270 - P273 - P301 + P312 - P501

Acute Tox. 4 Oral - Aquatic Chronic 3

13 - Non Combustible Solids

WGK 3