脱氧胆酸钠

C₂₄H₃₉NaO₄

414.55

3581950

MFCD00064139

Absorbance (10%, H₂O, 290 nm):≤0.25.
Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state (absorbance: <0.25 at 290 nm, 10% H₂O; aggregation number: 3-12; CMC: 2-6 mM; micellar weight: 1200-4900; pK_a: 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).
Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 3-12.

Toxicity: Harmful (C)

Do not use with Mn²⁺ in solution.

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C. Discard if bacterial or fungal growth is observed.

Pai, R., et al. Mol. Biol. Cell15, 2156.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥99% (TLC)

solid

micellar avg mol wt 1200-5000
micellar wt 1200-4900

Calbiochem^®

OK to freeze
desiccated (hygroscopic)

3 - 12
3-12

white

6.2

2 - 6 mM
2-6 mM (20-25℃)

16

ambient

15-25℃

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

FHHPUSMSKHSNKW-SMOYURAASA-M

5, 25 g in Glass bottle

GHS07

Warning

H302

P264 - P270 - P301 + P312 - P501

Acute Tox. 4 Oral

13 - Non Combustible Solids

WGK 1