Anti-α-2-Macroglobulin antibody produced in chicken

MFCD00162122

NA.41

α-2-Macroglobulin (validated) native human protein.
Immunogen Sequence: GI # 68765, sequence 1-1474

Anti-α-2-Macroglobulin antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200. It is also used for indirect ELISA.

A2M (α-2-macroglobulin) inhibits all four classes of proteinases by a unique ′trapping′ mechanism. This protein undergoes a conformational change when a proteinase binds and cleaves a specific peptide stretch called the "bait region" in the protein. This modified protein traps the bound proteinase It is involved in the clearance and degradation of Aβ, which is a major component of beta-amyloid deposits. Therefore, it is associated with Alzheimer′s disease (AD).

Solution in phosphate buffered saline containing 0.02% sodium azide.

chicken

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human, rat, mouse

Genway 15-288-20008F

indirect ELISA: suitable
western blot: suitable

MAHU

P01023

wet ice

−20℃

human ... A2M(2)

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12 - Non Combustible Liquids

WGK 1

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)