您的位置：首页 > 产品中心 > Anti-Fe65 antibody produced in rabbit
Anti-Fe65 antibody produced in rabbit
| 产品编号： | 4079736 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD06798441 |
| NACRES | NA.41 |
| Specificity【特异性】 | The antibody does not detect endogenous levels of Fe65. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acid residues 352-369 from mouse Fe65. |
| Application【应用】 | Anti-Fe65 antibody produced in rabbit is suitable for western blotting using mouse brain lysate. |
| Biochem/physiol Actions【生化/生理作用】 | Amyloid β A4 precursor protein-binding family B member 1 is a protein encoded by the APBB1 gene in humans and is mapped on human metaphase chromosomes to band 11p15. Fe65 is a neuronal adaptor protein that is involved in brain development, Alzheimer disease amyloid precursor protein (APP) signaling and proteolytic processing of APP. It participates in various processes by recruiting various interacting partners to form functional complexes and acts as a novel regulator of neurite outgrowth. Fe65 significantly alters actin dynamics and mitochondrial function in neuronal cells. |
| Physical form【外形】 | Solution in phosphate buffered saline containing 1.0 mg/mL bovine serum albumin and 0.05% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 97 kDa |
| species reactivity | mouse |
| technique(s) | western blot: suitable using mouse brain lysate |
| UniProt accession no.【UniProt登记号】 | Q9QXJ1 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Apbb1(11785) |
