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Anti-NOS3 (Ab-1177) antibody produced in rabbit
产品别名
Anti-NOS3 (Ab-1177) antibody produced in rabbit
Anti-ENOS antibody produced in rabbit
Anti-nitric oxide synthase 3 (endothelial cell) antibody produced in rabbit
Anti-ECNOS antibody produced in rabbit
基本信息
| MDL number | MFCD00675266 |
| NACRES | NA.41 |
| General description【一般描述】 | NOS3 (nitric oxide synthase 3) is located on human chromosome 7q36. |
| Immunogen【免疫原】 | Peptide sequence around aa. 1175-1179 (T-Q-S-F-S), according to the protein NOS3. |
| Application【应用】 | Anti-NOS3 (Ab-1177) antibody has been used in western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | Modifications in the NOS3 (nitric oxide synthase 3) gene leads to erectile dysfunction susceptibility, age of onset and severity. In heart, NOS3 helps in NO (nitric oxide) synthesis. It also controls vascular tone and blood pressure. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~140 kDa |
| species reactivity | human, rat, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (T-Q-S-F-S) |
| NCBI accession no.【NCBI登记号】 | NP_000594.2 |
| UniProt accession no.【UniProt登记号】 | P29474 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NOS3(4846) |
产品说明
| Target description【目标描述】 | Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
