| General description【一般描述】 | CellASIC ® ONIX2 Microfluidic System is an automated platform for precise manipulation of multiple key cell culture parameters, enabling measurement of cellular responses to pre-programmed media, temperature, and gas environment changes. It provides detailed information about live cell processes with ultra-high quality images and complete environment control. The system utilizes high quality, optically clear microfluidic plates and intuitive software, while integrating with a broad range of inverted microscopes to allow continuous, high magnification observation of live cells—as they react to their environment in time. Includes:- Controller System: Small footprint, integrated microincubator controller maintains fluid movement, reagent additions, temperature, and gas conditions.
- Microfluidic Plates: Application specific plates bring new cell culture capabilities for live cell imaging.
- Manifold: Low-profile, high quality, high optical clarity culture chambers and manifold, mount easily on an inverted microscope—without the need for a bulky environmental chamber.
- Software: Intuitive software enables quick and easy set-up of detailed protocols for truly automated hands-free cell culture.
Controller System: - Automatically control flow rates, gas and temperature shifts, standing gradients, nutrient/drug additions, and media changes.
- Eight critical cell culture parameters can be controlled by the system.
- Temperature, oxygen level, growth factors, humidity, pH, osmolality, glucose, ECM and adhesion.
Advantages of the CellASIC® ONIX2 microfluidic plates:- High resolution imaging through optical glass bottom and chamber structures.
- Ability to run multiple independent experiments simultaneously.
- Continuous access to nutrients and ongoing removal of waste, promoting optimal cell health.
Manifold Advantages:- Manifold seals to the microfluidic plate via “one-touch” vacuum mechanism.
- Pressure-driven flow of liquids to the cell chamber provides high precision even at very small volumes.
- No contact between the flow system and the biological solutions (on the plate) prevents contamination.
- Low-profile manifold is easy to adapt to any inverted microscope stage.
The software offers:- Clearly defined protocols with all experimental parameters saved in one file.
- Convenience and reproducibility.
- Consistency and reliability.
- Error checking, self test, and data logging all make for better troubleshooting and serviceability.
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