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SGK1 (δ1-60, S422D), active human
| 产品编号： | 4080574 |
| 规格： | recombinant, expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged), buffered aqueous solution |
| 包装规格： | 2 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD03458482 |
| NACRES | NA.32 |
| General description【一般描述】 | The serum- and glucocorticoid-regulated kinase (SGK1) is a member of the AGC kinase family and the gene encoding it is localized on human chromosome 6q23. |
| Biochem/physiol Actions【生化/生理作用】 | The serum- and glucocorticoid-regulated kinase (SGK1) has a role in the hormonal regulation of ion channels and pumps. It has been associated with cancers. The protein modulates nitric oxide production by activating NO synthase. SGK1 protects cells from apoptosis and oxidative stress. Kinase assays. |
| Unit Definition【单位定义】 | One unit of SGK1 = 1 nmol phosphate incorporated into crosstide substrate peptide in one minute. |
| Physical form【外形】 | Solution in 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 0.15 M NaCl, 0.03% Brij® L23, 1 mM benzamidine, 0.2 mM PMSF. and 270 mM sucrose. |
| Legal Information【法律信息】 | Brij is a registered trademark of Croda International PLC |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged) |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~48 kDa by SDS-PAGE |
| UniProt accession no.【UniProt登记号】 | O00141 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... SGK1(6446) |
