Anti-Human Hemoglobin antibody produced in rabbit

MFCD00162411

HBB (hemoglobin subunit β) codes for a β globin that consists of three exons. This gene is located on human chromosome 11p15. HBB is a serum protein that belongs to the histone-like protein family.

Hemoglobin isolated from normal adult human red blood cells and treated to remove lipoproteins.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Anti-Human Hemoglobin antibody produced in rabbit was used for immunoblotting using crude human cerebellar protein extracts and membrane extracts of human RBC. It was used for immunohistochemistry of human tongue cancer samples.
Anti-Human Hemoglobin antibody has been used in pulse chase experiments and western blotting.

Hemoglobin (Hb) is oxygen-binding metalloprotein that is present in the red blood cells. The most abundant Hb is HbA tetramer that is made up of two α, two β chains and the nonprotein heme group. The heme group contains iron ion and a porphyrin ring. Mutations in Hb gene result in hemoglobinopathies, the best known being sickle-cell disease and thalassemias.
HBB (hemoglobin subunit β) participates in oxygen transport from the lung to various peripheral tissues. Mutation in HBB result in Sickle cell disease (SCD). Overexpression of HBB has been observed in patients with periodontal disease.

treated to remove lipoproteins

rabbit

200

unconjugated

whole antiserum

primary antibodies

polyclonal

15 mM sodium azide

human

indirect ELISA: 1:8,000

P68871

dry ice

−20℃

human ... HBB(3043)

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