Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit

MFCD03454775

BACE-1 (β-site APP cleaving enzyme, Asp2 or memapsin 2) is known as β-secretase. BACE-1 is highly expressed in neurons, the major site of Aβ generation. BACE-1 is localized within the Golgi and endosomal compartments, among the several intracellular sites where Aβ is thought to be produced. It constitutes the predominant β-secretase activity in human brain tissue.

synthetic peptide corresponding to the C-terminus of human BACE-1 (amino acids 485-501).

Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit has been used in western blotting.

Overexpression of β-site APP cleaving enzyme (BACE-1) leads to increased β-secretase activity while displaying appropriate cleavage site specificity for amyloid precursor protein (APP).

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen 70 kDa

human

recombinant expression
Learn more about Antibody Enhanced Validation

microarray: suitable
western blot: 1:1,000 using a whole cell extract from the human kidney HEK293 cell line stably transfected with human BACE-1

P56817

dry ice

−20℃

human ... BACE1(23621)

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12 - Non Combustible Liquids

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