Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit

MFCD01092427

NA.41

Nitric Oxide Synthase, Brain (NOS1) is mapped to human chromosome 12q24.22. The NOS isoform found in neurons is a 150 kDa protein. It is also termed as brain NOS (bNOS). Human bNOS and endothelial NOS (eNOS) share 52% amino acid identity, and rat and human bNOS share 93% amino acid identity.

synthetic peptide corresponding to nitric oxide synthase (NOS) of rat brain origin (bNOS, amino acids 251-270) conjugated to KLH. The immunogen sequence is highly conserved in human bNOS.

Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit has been used in:

• double immunolabelling,
• immunofluorescence
• western blotting

Nitric Oxide Synthase, Brain (bNOS) is present also in skeletal muscle, where it is complexed with dystrophin and is absent in Duchenne muscular dystrophy (DMD). Neuronal and endothelial NOS are constitutively expressed and are dependent on Ca²⁺ calmodulin for nitric oxide (NO) production.

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

rabbit

200

unconjugated

IgG fraction of antiserum

primary antibodies

polyclonal

buffered aqueous solution

antigen 150-160 kDa

human, rat

microarray: suitable
western blot: 1:10,000 using rat brain extract

P29475

dry ice

−20℃

human ... NOS1(4842)
rat ... Nos1(24598)

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12 - Non Combustible Liquids

WGK 2