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Anti-Sodium Channel PN1 antibody produced in rabbit
| 产品编号： | 4080989 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 0.2 ML |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD02686628 |
| NACRES | NA.41 |
| General description【一般描述】 | Sodium channel protein type 9 subunit alpha (SCN9A) is encoded in human chromosome location 2q24.3. SCN9A is also called the Nav1.7. Sodium channel protein type 9 subunit alpha, (SCN9A) encodes nine isoforms in human and they are majorly expressed in cells of peripheral nervous system. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 446-460 of rat PN1 (with additional N-terminal cysteine). This epitope is highly conserved in rabbit and human. |
| Biochem/physiol Actions【生化/生理作用】 | They function to generate and conduct electrical impulses in neuronal membranes. SCNA9 mutations is associated with epilepsy in infant dravet syndrome. Nonsense mutations in SCNA9 gene leads to loss sensation towards pain. Missense mutations in SCNA9 results in primary erythermalgia and paroxysmal extreme pain disorder. |
| Physical form【外形】 | Lyophilized from a solution containing phosphate buffered saline, pH 7.4, 1% bovine serum albumin, and 0.05% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | rat |
| technique(s) | western blot (chemiluminescent): 1:200-1:400 |
| UniProt accession no.【UniProt登记号】 | O08562 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SCN9A(6335) rat ... Scn9a(78956) |
