Anti-Endothelin Receptor B antibody produced in rabbit

MFCD02677992

NA.41

Endothelin Receptor B (EDNRB) is a G-protein coupled receptor and that consists of seven transmembrane domains. EDNRB gene is located on the human chromosome at 13q22.3.

synthetic peptide corresponding to amino acids 298-313 of rat endothelin receptor type B. The epitope is identical in all known vertebrate ET-B receptors

Anti-Endothelin Receptor B antibody produced in rabbit has been used in immunohistochemistry (1:100).

EDNRB Endothelin receptor type B (ETB) plays a pivotal role in oesophageal cancer and may act as a therapeutic target for this intractable malignancy. It has a novel role in oligodendroglioma proliferation and acts as a potential therapeutic alternative for oligodendrogliomas. Lower expression of ETB receptor responsiveness is associated with polycystic ovary syndrome (PCOS) and may reflect lower endothelial-mediated vasodilatation independent of generally lower vascular reactivity.
Mutations in the EDNRB gene are associated with Hirschsprung disease.

Lyophilized at 0.8 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

lyophilized powder

rat

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100
western blot (chemiluminescent): 1:200

P21451

dry ice

−20℃

rat ... Ednrb(50672)

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GHS07

Warning

H315 - H319 - H335 - H412

P273 - P302 + P352 - P305 + P351 + P338

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Respiratory system

11 - Combustible Solids

WGK 3