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Neurotrophin-3 human
| 产品编号： | 4082312 |
| 规格： | recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture, >97% (SDS-PAGE) |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Neurotrophin-3 human
HDNF
NT-3
NTF3
基本信息
| MDL number | MFCD00212404 |
| NACRES | NA.32 |
| General description【一般描述】 | NTF3 (neurotrophin 3) is a neurotrophic factor belonging to the NGF (nerve growth factor) family. This protein is made up of 257 amino acids, with a prepro region of 138 amino acids and the mature sequence of 119 residues. |
| Application【应用】 | Neurotrophin-3 human has been used in the magnetic sorting of oligodendrocyte progenitor cells. |
| Biochem/physiol Actions【生化/生理作用】 | Neurotrophin-3 (13.6 kDa or 27.2 kDa dimer) is a member of the neurotrophin family. It has identical amino acid sequence in human, mouse, and pig with full cross-reactivities. NT-3 is important in development and maintenance of neuronal populations and promotes differentiation of neural crest derived sensory and sympathetic neurons. It is critical for proprioceptive 1a afferent neurons, which relay information from peripheral muscle spindles to motoneurons, sending projections to spinocerebellar neurons. NT-3 is also critical in the superior cervical and nodose ganglia. |
| Physical form【外形】 | Lyophilized from a 0.2 m filtered solution in phosphate buffered saline (PBS) containing 50 μg of bovine serum albumin (BSA) per 1 μg of cytokine. |
| Analysis Note【分析说明】 | The biological activity is measured in a cell proliferation assay using a TrkB-transfected cell line BaF-TrkB-BD. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in baculovirus infected Sf21 cells |
| Assay【测定】 | >97% (SDS-PAGE) |
| form【形式】 | lyophilized powder |
| potency【效能】 | 1-40 ng/mL EC50 |
| packaging【包装】 | pkg of 5 μg |
| technique(s) | cell culture | mammalian: suitable |
| impurities【杂质】 | endotoxin, tested |
| UniProt accession no.【UniProt登记号】 | P20783 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NTF3(4908) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
