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Anti-phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor® 488
| 产品编号： | 4082391 |
| 规格： | clone 3H10, from mouse, ALEXA FLUOR® 488 |
| 包装规格： | 100 TESTS |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor® 488
H3 histone, family 3A, H3S10P, Histone H3 (phospho S10), H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B)
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. |
| Specificity【特异性】 | Broad species cross-reactivity is expected. Histone H3 phosphorylated at Ser10 |
| Immunogen【免疫原】 | Epitope: Ser10 A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3. |
| Application【应用】 | Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Alexa Fluor® 488, is a Mouse Monoclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p, is labeled with Alexa Fluor Research Category Epigenetics & Nuclear Function Apoptosis & Cancer Research Sub Category Histones Cell Cycle, DNA Replication & Repair |
| Quality【质量】 | Evaluated by Flow Cytometry with Jurkat cells. |
| Physical form【外形】 | Purified mouse IgG1k conjugated to Alexa Fluor® 488 in PBS with 15mg/mL BSA and less than 0.09% sodium azide. Protein G Purified |
| Analysis Note【分析说明】 | Control Jurkat Cells |
| Legal Information【法律信息】 | ALEXA FLUOR is a registered trademark of Life Technologies |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | ALEXA FLUOR® 488 |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 3H10, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NM_003493 |
| UniProt accession no.【UniProt登记号】 | Q16695 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... HIST1H3F(8968) |
产品说明
| Target description【目标描述】 | 17 kDa observed |
| Storage and Stability【储存及稳定性】 | Maintain refrigerated at 2-8oC in undiluted aliquots for up to 6 months from date of receipt. Protect from light. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
