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Anti-Rho (-A, -B, -C) Antibody, clone 3L74, rabbit monoclonal
| 产品编号： | 4082521 |
| 规格： | culture supernatant, clone 3L74, Upstate® |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Rho (-A, -B, -C) Antibody, clone 3L74, rabbit monoclonal
ras homolog
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Rho proteins belong to the Ras super family of low molecular weight GTPases, which includes RAS, RHO, RAB, RAN, RAD and ARF. These small GTP binding proteins function as molecular switches that regulate a multitude of biological processes including cell proliferation, apoptosis, differentiation, cytoskeletal reorganisation, and membrane trafficking. |
| Specificity【特异性】 | Broad species cross-reactivity expected based on sequence homology Recognizes Rho (-A, -B, -C) |
| Immunogen【免疫原】 | KLH-conjugated, synthetic peptide (SYPDTDVILMCFSIDSPDSLENKK) corresponding to amino acids 73-94 of human Rho (-A, -B, -C), with two terminal lysines added to increase peptide solubility |
| Application【应用】 | Research Sub Category Cytoskeletal Signaling Research Category Signaling This Anti-Rho (-A Antibody, -B, -C), clone 3L74 is validated for use in WB for the detection of Rho (-A, -B, -C). Western Blot Analysis: A 1:1000-1:4000 dilution of this lot detected Rho (-A, -B, -C) in RIPA lysates from human HL-60 and rat PC-12 cells. This antibody also recognized recombinant RhoA protein, but not recombinant rac1 or cdc42 proteins. |
| Quality【质量】 | routinely evaluated by immunoblot on modified RIPA lysates from HL-60 cells |
| Linkage【联系】 | Replaces: 05-822 |
| Physical form【外形】 | Cultured supernantant in 0.05% sodium azide |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | culture supernatant |
| antibody product type | primary antibodies |
| clone【克隆】 | 3L74, monoclonal |
| species reactivity | human, rat |
| manufacturer/tradename | Upstate® |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NM_001664 |
| UniProt accession no.【UniProt登记号】 | P61586 |
| shipped in【运输】 | dry ice |
| Gene Information | human ... RHOA(387) |
产品说明
| Target description【目标描述】 | Mr 22kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
