Anti-RhoG Antibody, clone 1F3 B3 E5

32160702

NA.41

RhoG (ARGH) is a member of the Ras super-family of small G-proteins and a member of the Rac subfamily of Rho Family of GTPases. RhoG is a small G-protein (GTPase) who is activated by a GEF (guanine nucleotide exchange factor). The GEF displaces GDP from the binding site of RhoG and allows GTP to bind in it place rendering the protein active. This active RhoG binds downstream effector molecules that include ELMO and DOCK180. RhoG then cleaves GTP to GDP making it inactive. RhoG is believed to be crucial for integrin-mediated Rac activation and cell spreading. RhoG is believed to be active upstream of Rac and work independently of Rac.

Recognizes RhoG

KLH synthetic peptide encompassing amino acids CQQDGVKEVFAEAVRAVLNPT (RhoG 160-180)

Anti-RhoG Antibody, clone 1F3 B3 E5 is an antibody against RhoG for use in WB.

Routinely evaluated by western blot on NIH/3T3 cell lysate.

Purified mouse monoclonal IgG2b in storage buffer containing PBS with 0.05% sodium azide.
Protein G Purified
Format: Purified

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

100

mouse

purified antibody

primary antibodies

1F3 B3 E5, monoclonal

rat, human, mouse

Upstate^®

western blot: suitable

IgG2bκ

NM_001665

P84095

wet ice

21 kDa

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12 - Non Combustible Liquids

WGK 1