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InSolution Y-27632, Sterile-Filtered, Cell Culture-Tested-CAS 146986-50-7-Calbiochem
| 产品编号： | 4083556 |
| 规格： | InSolutionTM Y-27632, Sterile-Filtered, Cell Culture-Tested, CAS 146986-50-7, is a 10 mM sterile-filtered solution of Y-27632 in H2O. Acts as an inhibitor of Rho kinases (Ki = 140 nM for p160ROCK). |
| CAS NO： | 146986-50-7 |
| 包装规格： | 2 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4083556 | 2 MG | 4570 |
产品别名
146986-50-7
InSolution Y-27632, Sterile-Filtered, Cell Culture-Tested-CAS 146986-50-7-Calbiochem
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H21N3O · 2HCl |
| Molecular weight | 320.26 |
| General description【一般描述】 | Ready to use, cell culture-tested, suitable for stem cell applications. Acts as a highly potent, cell-permeable, reversible, and selective inhibitor of Rho-associated protein kinases (Ki = 140 nM for p160ROCK). Also shown to improve survival of human stem cells especially during cell culture passage and manipulation. A 10 mM (2 mg/591 µL) sterile-filtered solution of Y-27632 in H₂O. |
| Application【应用】 | InSolution |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target ROCK |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Physical form【外形】 | A 10 mM (2 mg/591 µL) sterile-filtered solution of Y-27632 (Cat. No. 688000) in H₂O. |
| Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. |
| Other Notes【其他说明】 | Li X. et al, et. Al., 2009. Human Reproduction, 24, 580. Chitaley, K., et al. 2001. Nat. Med.7, 119. Davies, S.P., et al. 2000. Biochem. J.351, 95. Narumiya, S., et al. 2000. Methods Enzymol.325, 273. Hirose, M., et al. 1999. J. Cell Biol.141, 1625. Maekawa, M., et al. 1999. Science.285, 895. Uehata, M., et al. 1997. Nature.389, 990. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles protect from light |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11?,12?/m1/s1 |
| InChI key | IYOZTVGMEWJPKR-VOMCLLRMSA-N |
| packaging【包装】 | Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
