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CL-82198-CAS 1188890-36-9-Calbiochem
| 产品编号： | 4083778 |
| 规格： | A selective inhibitor of MMP-13 (IC50 = 10 μM). |
| CAS NO： | 1188890-36-9 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
1188890-36-9
CL-82198-CAS 1188890-36-9-Calbiochem
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H22N2O3 · xHCl |
| Molecular weight | 302.37 (free base basis) |
| General description【一般描述】 | A selective inhibitor of MMP-13 (IC50 = 10 µM) that does not appear to act by chelating Zn2+. Binds within the entire S1′ pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE. A selective inhibitor of MMP-13 (IC50 = 10 µM). Binds to the S1′ pocket of MMP-13 with its morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE. |
| Biochem/physiol Actions【生化/生理作用】 | Target IC50: 10 µM against MMP-13 Product does not compete with ATP. Reversible: no Primary Target MMP-13 Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C. |
| Other Notes【其他说明】 | Chen, J.M., et al. 2000. J. Am. Chem. Soc.122, 9648. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥97% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) |
| color【颜色】 | light yellow |
| solubility【溶解性】 | water: 25 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
