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Flt-3 Inhibitor-CAS 301305-73-7-Calbiochem
| 产品编号： | 4083780 |
| 规格： | The Flt-3 Inhibitor, also referenced under CAS 301305-73-7, controls the biological activity of Flt-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
| CAS NO： | 301305-73-7 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4083780 | 5 MG | 3120 |
产品别名
301305-73-7
Flt-3 Inhibitor-CAS 301305-73-7-Calbiochem
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H20N2O4S |
| Molecular weight | 360.43 |
| MDL number | MFCD00617269 |
| General description【一般描述】 | A cell-permeable thienylcarboxamide compound that acts as a potent, ATP-competitive, and highly selective Flt-3 inhibitor (IC50 = 42 nM) with little effect against a panel of 22 other kinases (IC50 ≥3 µM). Shown to exhibit antiproliferative properties against the human acute myelogenous leukemia cell line MV4-11 (IC50 = 340 nM) expressing constitutively active Flt-3. |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Target IC50: 42 nM against Flt-3 Reversible: no Product competes with ATP. |
| Warning【警告】 | Toxicity: Irritant (B) |
| Other Notes【其他说明】 | Patch, R.J., et al. 2006. Bioorg. Med. Chem. Lett.16, 3282. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: <4 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
