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ErbB2 Inhibitor II-CAS 928207-02-7-Calbiochem
| 产品编号： | 4083836 |
| 规格： | The ErbB2 Inhibitor II, also referenced under CAS 928207-02-7, controls the biological activity of ErbB2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
| CAS NO： | 928207-02-7 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
928207-02-7
ErbB2 Inhibitor II-CAS 928207-02-7-Calbiochem
4-(3-Phenoxyphenyl)-5-cyano-2H-1,2,3-triazole
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H10N4O |
| Molecular weight | 262.27 |
| General description【一般描述】 | A cell-permeable triazole compound that targets the ATP-binding site of erbB2/HER2 and reduces the phosphorylation of erbB2 in MDA-MB-453 cells (IC50 = 6.6 µM), but not that of the overexpressed erbB1 in MDA-MB-468 cells even at concentrations as high as 100 µM. Shown to suppress MDA-MB-453 growth with an IC50 of 30.9 µM. |
| Warning【警告】 | Toxicity: Irritant (B) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C. |
| Other Notes【其他说明】 | Cheng, Z. Y., et al. 2007. Bioorg. Med. Chem.15, 1533. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: 50 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
