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Gβγ Modulator II, Gallein-CAS 2103-64-2-Calbiochem

产品编号:4083846
规格:A cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ~400 nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities.
CAS NO:2103-64-2
包装规格:5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40838465 MG2200
产品别名

2103-64-2

Gβγ Modulator II, Gallein-CAS 2103-64-2-Calbiochem

4,5-Dihydroxyfluorescein, dihydrate, 2-(3,4,5-Trihydroxy-6-oxoxanthen-9-yl)-benzoic acid, dihydrate

基本信息
Empirical Formula【经验(实验)分子式】
C20H12O7 · 2H2O
Molecular weight
400.34
General description【一般描述】
A cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ~400 nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities. Reported to exhibit in vivo prophylactic efficacy against carrageenan-induced neutrophil recruitment and tissue swelling in a murine paw edema model via either intraperitoneal or oral administration.
Warning【警告】
Toxicity: Standard Handling (A)
Other Notes【其他说明】
Lehmann, D.M., et al. 2008. Mol. Pharmacol.73, 410.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥90% (HPLC)
form【形式】
solid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
protect from light
color【颜色】
burgundy
solubility【溶解性】
DMSO: 10 mg/mL
shipped in【运输】
ambient
storage temp.【储存温度】
2-8℃
InChI
1S/C20H12O7/c21-13-7-5-11-17(15(13)23)26-18-12(6-8-14(22)16(18)24)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,21-24H
InChI key
PHLYOKFVXIVOJC-UHFFFAOYSA-N
packaging【包装】
5 mg in Plastic ampoule
Packaged under inert gas
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 1
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