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Hedgehog Antagonist VIII-CAS 330796-24-2-Calbiochem
| 产品编号： | 4083859 |
| 规格： | The Hedgehog Antagonist VIII, also referenced under CAS 330796-24-2, controls the biological activity of Hedgehog. This small molecule/inhibitor is primarily used for Cell Signaling applications. |
| CAS NO： | 330796-24-2 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
330796-24-2
Hedgehog Antagonist VIII-CAS 330796-24-2-Calbiochem
1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl)methyl)-urea, Hh Signaling Antagonist VIII
Hh Signaling Antagonist VIII, 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl)methyl)-urea
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H15ClF4N4O2 |
| Molecular weight | 490.84 |
| General description【一般描述】 | A cell-permeable quinazolinyl-urea compound that is shown to potently inhibit OCT-Shh-stimulated Gli transcription activity in a 10t1/2(s12) cell-based Luciferase reporter assay (IC50 = 70 nM). |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C0. Stock solutions are stable for up to 3 months at -20°C. |
| Other Notes【其他说明】 | Brunton, A.A., et al. 2008. J. Med. Chem.51, 1108. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | clear slightly yellow |
| solubility【溶解性】 | DMSO: 100 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
