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Prolyl Endopeptidase Inhibitor II-CAS 108708-25-4-Calbiochem
| 产品编号： | 4083942 |
| 规格： | The Prolyl Endopeptidase Inhibitor II, also referenced under CAS 108708-25-4, controls the biological activity of Prolyl Endopeptidase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. |
| CAS NO： | 108708-25-4 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
108708-25-4
Prolyl Endopeptidase Inhibitor II-CAS 108708-25-4-Calbiochem
Z-PP-CHO
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H22N2O4 |
| Molecular weight | 330.38 |
| General description【一般描述】 | A cell-permeable dipeptide aldehyde that acts as a specific, potent, slow and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki = 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively). Reported to form a hemiacetal with the active-site serine. A cell-permeable dipeptide aldehyde that acts as a specific, potent, slow, and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki = 350 pM and 500 pM for mouse brain and human brain, respectively). Reported to form a hemiacetal with the active site serine of the enzyme. |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Target Ki: 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively Cell permeable: yes Primary Target Mouse brain prolylendooeotidase Reversible: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | Z-Pro-Pro-CHO |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
| Other Notes【其他说明】 | Fülöp, V., et al. 1998. Cell94, 161. Kahyaoglu, A., et al. 1997. Biochem. J.322, 839. Bakker, A.V., et al. 1990. Biochem. J.271, 559. Wilk, S., and Orlowski, M. 1983. J. Neurochem.41, 69. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥97% (HPLC) |
| form【形式】 | oil |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | colorless to off-white |
| solubility【溶解性】 | DMSO: 10 mg/mL DMF: soluble ethyl acetate: soluble |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
