Proteasome Substrate VI, Fluorogenic-CAS 90468-18-1-Calbiochem

C₃₃H₄₄N₁₀O₇ · 2HCl

765.69

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome. Also reported to be a specific substrate for cathepsin B.
A fluorogenic substrate for assaying trypsin-like activity of proteasome. Also serves as a substrate for cathepsin B. Excitation max: 360-380 nm; emission max.: 430-460 nm.

Product does not compete with ATP.
Primary Target
Proteasome
Reversible: no
Cell permeable: no

Toxicity: Standard Handling (A)

Z-Ala-Arg-Arg-AMC

Supplied as hydrochloride salt.

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C

Geier, E., et al. 1999. Science283, 978.
Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥98% (HPLC)

solid

Calbiochem^®

OK to freeze
protect from light

white to off-white

DMSO: 200 mg/mL
80% acetic acid: 50 mg/mL
methanol: soluble

λ_ex ~380  nm
λ_em ~460 nm

ambient

−20℃

5 mg in Glass bottle
Packaged under inert gas

11 - Combustible Solids

WGK 1