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JNK Inhibitor IX-CAS 312917-14-9-Calbiochem
| 产品编号： | 4084093 |
| 规格： | The JNK Inhibitor IX, also referenced under CAS 312917-14-9, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. |
| CAS NO： | 312917-14-9 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4084093 | 5 MG | 3120 |
产品别名
312917-14-9
JNK Inhibitor IX-CAS 312917-14-9-Calbiochem
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-1-naphthamide
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H16N2OS · xH2O |
| Molecular weight | 332.42 (anhydrous basis) |
| General description【一般描述】 | A thienylnaphthamide compound that acts as a potent and ATP binding site-targeting inhibitor of JNK2 and JNK3 (pIC50 = 6.5 and 6.7, respectively) with little or no activity against JNK1, p38α, and a panel of more than 30 other kinases (pIC50<5.0). In contrast, SP600125 offers little selectivity between JNK1 and JNK3 (pIC50 = 6.4 and 5.9, respectively) under the same assay conditions. |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target JNK2 and JNK3 Reversible: no Product competes with ATP. pIC50 = 6.5 and 6.7, against JNK2 and JNK3, respectively Cell permeable: no |
| Warning【警告】 | Toxicity: Irritant (B) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
| Other Notes【其他说明】 | Angell, R.M., et al. 2007. Bioorg. Med. Chem. Lett.17, 1296. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | tan |
| solubility【溶解性】 | DMSO: 10 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
