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InSolution PKR Inhibitor-CAS 608512-97-6-Calbiochem
| 产品编号： | 4084239 |
| 规格： | The InSolution |
| CAS NO： | 608512-97-6 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4084239 | 5 MG | 2570 |
产品别名
608512-97-6
InSolution PKR Inhibitor-CAS 608512-97-6-Calbiochem
Double-stranded RNA-activated Protein Kinase Inhibitor I, Double-stranded RNA-dependent Protein Kinase Inhibitor I, EIF2AK2 Inhibitor I, C16
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H8N4OS |
| Molecular weight | 268.29 |
| MDL number | MFCD06735404 |
| General description【一般描述】 | An imidazolo-oxindole compound that acts as a potent, ATP-binding site directed inhibitor of PKR. Shown to effectively inhibit RNA-induced PKR autophosphorylation (IC50 = 210 nM) and rescue PKR-dependent translation block (IC50 = 100 nM). The solid form of this compound (Cat. No. 527450) is also available. |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Primary Target PKR Reversible: yes |
| Warning【警告】 | Toxicity: Irritant (B) |
| Physical form【外形】 | A 50 mM (5 mg/373 µL) solution of PKR Inhibitor (Cat. No. 527450) in DMSO. |
| Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. |
| Other Notes【其他说明】 | Zhu, P.J., et al. 2011. Cell147, 1384. Jammi, N.V., et al. 2003. Biochem. Biophys. Res. Commun.308, 50. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥90% (HPLC) |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles desiccated (hygroscopic) protect from light |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mg in Glass bottle Packaged under inert gas |
