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SGK2 Active human
| 产品编号： | 4084414 |
| 规格： | ≥75% (SDS-PAGE), aqueous glycerol solution, recombinant, expressed in E. coli |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
SGK2 Active human
Serum/glucocorticoid-regulated kinase 2
基本信息
| MDL number | MFCD07371188 |
| NACRES | NA.32 |
| Application【应用】 | Kinase activity is measured as the molar amount of phosphate incorporated into the Akt/SGK substrate peptide (RPRAATF), per minute per mg protein at 30 ℃ using a final concentration of 50 μM [32P] ATP. |
| Biochem/physiol Actions【生化/生理作用】 | SGK2 is a member of the serum- and glucocorticoid-induced kinases (SGK) which are serine-threonine kinases and belong to the "AGC" kinase subfamily, which includes protein kinases A, G, and C and has SGK2 enhances Na+/K+-ATPase activity in a variety of cells. In addition, SGK2 mimics the function of SGK1 and SGK3 and participates in the regulation of renal epithelial Na+ channel ENaC activity. |
| Unit Definition【单位定义】 | One unit will incorporate one nanomole of phosphate into the AKT/SGK substrate peptide(RPRAATF) per minute at 30 ℃ and pH 7.2 using a final concentration of 50 μM [32P] ATP. |
| Physical form【外形】 | Supplied at 50 μL in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM dithiothreitol (DTT), 0.1 mM EGTA, and 30% glycerol. |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥75% (SDS-PAGE) |
| form【形式】 | aqueous glycerol solution |
| Specific Activity | 100 units/mg protein (Bradford) |
| mol wt【分子量】 | protein apparent mol wt ~66 kDa |
| UniProt accession no.【UniProt登记号】 | Q9HBY8 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... SGK2(10110) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
