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Fas Ligand, soluble human
| 产品编号： | 4084437 |
| 规格： | recombinant, expressed in HEK 293 cells, lyophilized powder |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Fas Ligand, soluble human
SuperFas Ligand
基本信息
| MDL number | MFCD01092558 |
| NACRES | NA.56 |
| Application【应用】 | ED50 = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFasL™ recognizes its receptor Fas (CD95) of the following species: human, rat, mouse. |
| Biochem/physiol Actions【生化/生理作用】 | Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1). Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation. |
| Legal Information【法律信息】 | SuperFas Ligand is a trademark of Alexis Biochemicals Corp. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in HEK 293 cells |
| Assay【测定】 | ≥95% (SDS-GE) |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | 32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions) 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions) |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no.【UniProt登记号】 | P48023 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... FASLG(356) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
