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20:0(2R-OH) Ceramide
| 产品编号： | 4084556 |
| 规格： | N-(2′-(R)-hydroxyarachidoyl)-D-erythro-sphingosine, powder |
| CAS NO： | 943147-54-4 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
943147-54-4
20:0(2R-OH) Ceramide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C38H75NO4 |
| Molecular weight | 610.01 |
| NACRES | NA.25 |
| General description【一般描述】 | Ceramides containing 2-hydroxy fatty acids (hFA) group are mainly found in the epidermis. 20:0(2R-OH) Ceramide is a 2R hydroxylated arachidic acid-containing ceramide. |
| Biochem/physiol Actions【生化/生理作用】 | Hydroxy fatty acid (hFA)-sphingolipids play a vital role in cell signaling. hFA-ceramides contribute to the permeability barrier function of the surface epithelium of the skin. Fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. Impaired function of FA2H causes nervous system disorders leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for PM02734, an antitumor drug to exhibit its activity. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 860819P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCCCCC)=O)CO |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860819P-5mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
