您的位置：首页 > 产品中心 > Anti-Rho (-A Antibody, -B, -C), clone 55
Anti-Rho (-A Antibody, -B, -C), clone 55
产品别名
Anti-Rho (-A Antibody, -B, -C), clone 55
Aplysia ras-related homolog 12, oncogene RHO H12, ras homolog gene family, member A, small GTP binding protein RhoA
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Rho proteins belong to the Ras super family of low molecular weight GTPases, which includes RAS, RHO, RAB, RAN, RAD and ARF. These small GTP binding proteins function as molecular switches that regulate a multitude of biological processes including cell proliferation, apoptosis, differentiation, cytoskeletal reorganization, and membrane trafficking. |
| Specificity【特异性】 | Recognizes Rho (-A, -B, -C), Mr 22 kDa. |
| Immunogen【免疫原】 | Recombinant human RhoA containing amino acids 1-155. Clone 55. |
| Application【应用】 | Immunocytochemistry: This antibody has been reported by an independent laboratory to detect Rho in cells via immunofluorescence. Research Sub Category Cytoskeletal Signaling Research Category Signaling Detect Rho (-A, -B, -C) using this Anti-Rho (-A Antibody, -B, -C), clone 55 validated for use in IC & WB. |
| Quality【质量】 | Routinely evaluated by western blot on RIPA lysates from Jurkat or HL-60 cells. Western Blot Analysis: 0.5-2 µg/mL of this lot detected Rho in RIPA lysates from HL-60 cells. A previous lot detected Rho in RIPA lysates from Jurkat cells. |
| Physical form【外形】 | Format: Purified Purified mouse monoclonal IgG1 in buffer containing BSA containing 0.09% sodium azide and 50% glycerol. Protein G Purified |
| Analysis Note【分析说明】 | Control HL-60 cell lysate. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 55, monoclonal |
| species reactivity | mouse, human, rat |
| manufacturer/tradename | Upstate® |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1 |
| NCBI accession no.【NCBI登记号】 | NP_001655 |
| UniProt accession no.【UniProt登记号】 | P61586 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... RHOA(387) |
产品说明
| Target description【目标描述】 | 22 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20ºC may cause glycerol-containing solutions to become frozen during storage. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
