p53 (1-363) C-terminal deletion human

NA.26

Human p53 protein is composed of 393 amino acid residues with several distinct regions. The N-terminal activation domain allows p53 protein to recruit the basal transcription machinery and activate the expression of target genes, whereas the core domain binds to target DNA in a sequence-specific manner and the majority of mutations found in human tumors occur in the region of the gene encoding this domain. The C-terminal domain is composed of predominantly basic residues and modification of the C-terminal basic domain, including acetylation, glycosylation and phosphorylation, is an essential mechanism for regulating p53 function.

Clear and colorless frozen liquid solution

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

human

expressed in insect cells

≥80% (SDS-PAGE)

frozen liquid

~41.8 kDa

pkg of 5 μg

850 μg/mL

clear colorless

NM_000546

P04637

dry ice

−70℃

human ... TP53(7157)

10 - Combustible liquids

WGK 1