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5β,6β-epoxycholestanol
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4085072 | 5 MG | 1100 |
产品别名
4025-59-6
5β,6β-epoxycholestanol
110805
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H46O2 |
| Molecular weight | 402.65 |
| NACRES | NA.25 |
| General description【一般描述】 | 5β,6β-epoxycholestanol (5β,6β-EC) is generated by cholesterol epoxidation and is a diastereoisomer of 5α,6α-epoxycholestanol (5α,6α-EC). |
| Application【应用】 | 5β,6β-epoxycholestanol may be used as a oxy-mix component in treating human colorectal adenocarcinoma CaCo-2 cells to test its effect on toll-like receptor (TLR) expression, in the preparation of langmuir monolayers for isotherm studies, as an internal standard for gas chromatography-mass spectrometry (GC–MS) chromatograms |
| Biochem/physiol Actions【生化/生理作用】 | 5β,6β-epoxycholestanol (5β,6β-EC) is associated with human carotid plaques and is not down-regulated by apolipoprotein A1 (apoA-I) protein. 5,6β-EC along with 5α,6α-epoxycholesterol and other oxysterols are reported to be associated with Alzheimer′s disease. It is catabolized by the enzyme cholesterol-5,6-epoxide hydrolase (ChEH) enzyme to 3β,5α,6β-triol. 5β,6β-EC elicits cytotoxic and inflammatory properties. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 700033P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | C[C@]12CC[C@H]([C@](CC[C@H](O)C3)(C)[C@]3(O4)[C@H]4C5)[C@@H]5[C@@H]1CC[C@@H]2[C@H](C)CCCC(C)C |
| InChI | 1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,25-,26-,27-/m1/s1 |
| InChI key | PRYIJAGAEJZDBO-DTLXENBRSA-N |
| packaging【包装】 | 5 mL PTFE Vial with Screw Cap (700033P-5mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
