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Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5

产品编号:4085192
规格:clone 5D11G5, Upstate®, from mouse
包装规格:200 μg
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4085192200 μg5520
基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
SMC1 is a ATPase and subunit of the multiprotein cohesin complex, a protein involved in chromosome segregation and in double-strand DNA break (DSB) repair. Serine 957 is phosphorylated by ATM in response to DSBs and is involved in the S-phase DNA damage checkpoint.
Specificity【特异性】
Predicted to cross-react with xenopus and bovine based on sequence homology
phospho-SMC1 (Ser957)
Immunogen【免疫原】
KLH-conjugated, synthetic peptide corresponding to amino acids 951-962 (SQEEGS[pS]QGEDS) of human SMC1
Application【应用】
Research Sub Category
Cell Cycle, DNA Replication & Repair
Detect phospho-SMC1 (Ser957) with Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5 (Mouse Monoclonal Antibody), that has been shown to work in WB.
Research Category
Epigenetics & Nuclear Function
Quality【质量】
routinely evaluated by immunoblot on RIPA lysates from irradiated GMO536 cells and hydroxyurea treated HEK293 cells
Physical form【外形】
Format: Purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Protein G Purified
Legal Information【法律信息】
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
purified antibody
antibody product type
primary antibodies
clone【克隆】
5D11G5, monoclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype【同位素/亚型】
IgG1
NCBI accession no.【NCBI登记号】
NM_006306
UniProt accession no.【UniProt登记号】
Q14683
shipped in【运输】
wet ice
Gene Information
human ... SMC1A(8243)
产品说明
Target description【目标描述】
Mr 150kDa
Storage and Stability【储存及稳定性】
2 years at -20°C
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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