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MART-1 human
| 产品编号： | 4085340 |
| 规格： | recombinant, expressed in E. coli, ≥90% (SDS-PAGE) |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
MART-1 human
Antigen LB39-AA
Antigen SK29-AA
Protein Melan-A
Melanoma antigen recognized by T-cells 1
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Melanoma-associated antigen recognized by T cells-1 (MART-1) (also known as Melan-A) is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. It is a transmembrane protein which is hydrophobic in nature. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. The protein is also expressed in melanoma tumors. Human MART-1 is purified by proprietary chromatographic techniques. |
| Biochem/physiol Actions【生化/生理作用】 | Melanoma-associated antigen recognized by T cells-1 (MART-1) has been shown to be essential for the functioning of glycoprotein-100 (gp100). |
| Physical form【外形】 | Lyophilized without additives. |
| Reconstitution【重悬】 | Reconstitute in water to a concentration 0.1-1 mg/mL. The solution can then be further diluted to other aqueous solutions. Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥90% (HPLC) ≥90% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | ~18.0 kDa |
| packaging【包装】 | pkg of 5 μg |
| impurities【杂质】 | endotoxin, tested |
| NCBI accession no.【NCBI登记号】 | Q16655 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MLANA(2315) |
