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CAY10526
产品别名
938069-71-7
CAY10526
4-Benzo[b]thiophen-2-yl-3-bromo-5-hydroxy-5H-furan-2-one
4-Benzo[b]thien-2-yl-3-bromo-5-hydroxy-2(5H)-furanone
4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H7BrO3S |
| Molecular weight | 311.15 |
| Biochem/physiol Actions【生化/生理作用】 | CAY10526 is a selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) expression. CAY10526 potently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells. CAY10526 significantly suppressed tumor growth and increased apoptosis in melanoma xenografts. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C1OC(C(C2=CC3=C(S2)C=CC=C3)=C1Br)O |
