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CH625
产品别名
123316-64-3
CH625
ZINC95910725
(2E)-1-(4-Hydroxy-2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
4,4′-Dihydroxy-2′,6′-dimethoxychalcone
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H16O5 |
| Molecular weight | 300.31 |
| Biochem/physiol Actions【生化/生理作用】 | CH625 is a potent and selective competitive inhibitor of CYP4X1 that decreases tumor burden, increases survival in glioma intracranial and subcutaneous model in rats. CH625 normalizes tumor vasculature in the C6 and GL261 gliomas through tumor-associated macrophages (TAMs) reprograming and inhibition of VEGF and TGF-β production. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
