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华蟾蜍精

Cinobufagin
产品编号:4086074
规格:≥98% (HPLC)
CAS NO:470-37-1
包装规格:5 mg,25 mg
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40860745 mg1010
408607425 mg3510
产品别名

470-37-1

华蟾蜍精

Cinobufagin

5β,20(22)-Bufadienolide-3β,16β-diol-14,15β-epoxy 16-acetate

14,15β-Epoxy-3β,16β-dihydroxy-5β,20(22)-bufadienolide 16-acetate, 5β,20(22)-Bufadienolide-3β,16β-diol-14,15β-epoxy 16-acetate

14,15β-Epoxy-3β,16β-dihydroxy-5β,20(22)-bufadienolide 16-acetate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C26H34O6
Molecular weight
442.54
MDL number
MFCD00056825
Biochem/physiol Actions【生化/生理作用】
Cinobufagin is a bufanolide steroid with anti-proliferative and pro-apoptotic effects as well as antinociception activity. It has been used in Chinese herbal medicine and has been shown to have clinical applications in a variety of cancers both as an anticancer agent and to reduce cancer pain. Cinobufagin was recently identified as novel expression-mimicker that exert in vitro as well as in vivo anti-AML efficacy against AML expressing mtRUNX1.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 2 mg/mL, clear
storage temp.【储存温度】
−20℃
SMILES string
C[C@]([C@@H](C(C=C1)=COC1=O)[C@H]2OC(C)=O)(CC[C@@]3([H])[C@@]4([H])CC[C@@]5([H])[C@@]3(CC[C@H](O)C5)C)[C@@]64[C@@H]2O6
InChI
1S/C26H34O6/c1-14(27)31-22-21(15-4-7-20(29)30-13-15)25(3)11-9-18-19(26(25)23(22)32-26)6-5-16-12-17(28)8-10-24(16,18)2/h4,7,13,16-19,21-23,28H,5-6,8-12H2,1-3H3/t16-,17+,18+,19-,21+,22-,23-,24+,25-,26-/m1/s1
InChI key
SCULJPGYOQQXTK-OLRINKBESA-N
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H300 + H310 + H330
Precautionary Statements
P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
Hazard Classifications【危险分类】
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
Storage Class Code【储存分类代码】
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
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