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双叶茶素
Diphyllin
产品别名
22055-22-7
双叶茶素
Diphyllin
NSC 309691
9-(1,3-Benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-naphtho[2,3-c]furan-1(3H)-one
9-(1,3-苯并二恶唑-5-基)-4-羟基-6,7-二甲氧基萘[2,3-c]呋喃-1(3H)-酮
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H16O7 |
| Molecular weight | 380.35 |
| MDL number | MFCD00808222 |
| PubChem Substance ID【PubChem化学物质编号】 | 329826058 |
| General description【一般描述】 | Diphyllin, a major glycoside compound, is a plant-derived lignan. It is present in Cleistanthus collinus. |
| Application【应用】 | Diphyllin has been used to study its antibacterial and antibiofilm activities against fish pathogens. |
| Biochem/physiol Actions【生化/生理作用】 | Diphyllin is a natural arylnaphthalene that exhibits potent anticancer and antiviral activities. It is a potent inhibitor of vacuolar H(+)-ATPase (V-ATPase) that inhibits lysosomal acidification in osteoclasts. Diphyllin has shown potential to be used in a novel treatment for bone problems characterized by excessive resorption. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to light brown |
| solubility【溶解性】 | DMSO: 5 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC1=C2C(C(OC2)=O)=C(C3=CC=C(OCO4)C4=C3)C5=CC(OC)=C(OC)C=C51 |
| InChI | 1S/C21H16O7/c1-24-15-6-11-12(7-16(15)25-2)20(22)13-8-26-21(23)19(13)18(11)10-3-4-14-17(5-10)28-9-27-14/h3-7,22H,8-9H2,1-2H3 |
| InChI key | VMEJANRODATDOF-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
