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EIDD-2801
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086113 | 5 MG | 1140 | |||
| 4086113 | 25 MG | 3360 |
产品别名
2349386-89-4
EIDD-2801
EIDD2801
EIDD 1931 5′-isopropylester
N4-Hydroxycytidine 5′-isopropylester
beta-D-N4-Hydroxycytidine 5′-isopropylester
EIDD 1931 prodrug
N4OHcyd ester
4-N-HO-Cyd ester
EIDD1931 prodrug
EIDD-1931 prodrug
N4-OHcyd ester
(oh)4Cyd lester
NHC ester
EIDD-1931 5′-isopropylester
EIDD1931 5′-isopropylester
EIDD 2801
((2R,3S,4R,5R)-3,4-Dihydroxy-5-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate
BHC ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H19N3O7 |
| Molecular weight | 329.31 |
| Biochem/physiol Actions【生化/生理作用】 | EIDD-2801 is an orally active, 5′-isopropylester prodrug form of the antiviral ribonucleoside analog N4-hydroxycytidine (NHC, EIDD-1931) with known anti-viral activity against SARS-CoV, SARS-CoV-2, RSV, influenza A & B (IAV & IBV), HCV, pestivirus, bovine viral diarrhoea virus (BVDV), Ebola (EBOV), Chikungunya (CHIKV), venezuelan equine encephalitis (VEEV). EIDD-2801 is efficiently hydrolyzed to NHC in vivo, being more orally bioavailable than NHC in nonhuman primates and ferrets, while maintaining similar oral bioavailability as NHC in mice. EIDD-2801 displays in vivo efficacy against pandemic and seasonal IAV strains in ferrets (lowest ED = 2.3 and 7 mg/kg b.i.d. p.o., respectively). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
