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Gemcabene
产品别名
183293-82-5
Gemcabene
6,6′-Oxybis(2,2-dimethylhexanoic acid)
CI-1027
PD72953
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H30O5 |
| Molecular weight | 302.41 |
| MDL number | MFCD00951832 |
| Biochem/physiol Actions【生化/生理作用】 | Gemcabene is an orally available lipid-regulating compound that induces both a cholesterol and triglyceride reduction by a mechanism of action not linked to agonist or antagonist activity on the PPAR-α receptors. Gemcabene down-regulates apoC-III expression. Gemcabene is primarily metabolized (glucuronidation) by UDP-glucuronosyltransferase2B7 (UGT2B7). Thus, is often used as a UGT2B7 substrate. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(O)C(CCCCOCCCCC(C(O)=O)(C)C)(C)C |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
