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GLX351322
产品别名
835598-94-2
GLX351322
2-[[2-[4-(2-Furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid ethyl ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H25N3O5S |
| Molecular weight | 431.51 |
| MDL number | MFCD05123600 |
| Biochem/physiol Actions【生化/生理作用】 | GLX351322 is a potent and selective inhibitor of NOX4 (NADPH oxidase 4). GLX351322 prevents ROS generation and cellular death, improves pancreatic beta cell function in high-fat diet fed C57Bl/6 mice. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(C1=C(NC(CN2CCN(C(C3=CC=CO3)=O)CC2)=O)SC4=C1CCC4)OCC |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
