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NSAH
产品别名
1099592-35-4
NSAH
2-Hydroxy-benzoic acid (2E)-2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H14N2O3 |
| Molecular weight | 306.32 |
| MDL number | MFCD00196698 |
| Biochem/physiol Actions【生化/生理作用】 | NSAH is a cell penetrant, potent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase). NSAH binds to catalytic site of hRRM1. It inhibits hRR in cells. NSAH exhibit potent cytotoxicity toward cancer cells, while demonstrated very moderate toxicity against normal blood progenitor cells. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC1=CC=CC=C1C(N/N=C/C2=C(C=CC=C3)C3=CC=C2O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
