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NSC59984
产品别名
803647-40-7
NSC59984
1-Methyl-4-[3-(5-nitro-2-furanyl)-1-oxo-2-propenyl]-piperazine
MLS000737358
1-(4-Methyl-1-piperazinyl)-3-(5-nitro-2-furanyl)-2-propen-1-one
(E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2yl)prop-2-en-1-one
CID 5356520
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H15N3O4 |
| Molecular weight | 265.27 |
| MDL number | MFCD29905462 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825487 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | NSC59984 targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells. NSC59984 depletes a gain of function (GOF p53 mutants. NSC59984 is not cytotoxic against normal cells. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | yellow to brown |
| solubility【溶解性】 | DMSO: 5 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN1CCN(C(/C=C/C2=CC=C([N+]([O-])=O)O2)=O)CC1 |
| InChI | 1S/C12H15N3O4/c1-13-6-8-14(9-7-13)11(16)4-2-10-3-5-12(19-10)15(17)18/h2-5H,6-9H2,1H3/b4-2+ |
| InChI key | QKTRIGNWBRHBFV-DUXPYHPUSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
