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Oxanthroquinone G01
产品别名
1616622-15-1
Oxanthroquinone G01
G01
9,10-Dihydro-8-hydroxy-3-methoxy-1,7-dimethyl-9,10-dioxo-2-anthracenecarboxylic acid ethyl ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H18O6 |
| Molecular weight | 354.35 |
| Biochem/physiol Actions【生化/生理作用】 | Oxanthroquinone G01 is a potent inhibitor of KRAS and NRAS plasma membrane localization that potently inhibits proliferation of KRAS transformed cancer cells. Oxanthroquinone G01 also inhibits recycling of epidermal growth factor receptor and transferrin receptor, but has no influence on cholera toxin internalization. It also increases cellular levels of sphingomyelin and and ceramide. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | faint yellow to dark orange |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C1C2=C(C=C(OC)C(C(OCC)=O)=C2C)C(C3=CC=C(C)C(O)=C31)=O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
