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PhiKan083 hydrochloride
产品别名
1050480-30-2
PhiKan083 hydrochloride
PK-083 hydrochloride
9-Ethyl-N-methyl-9H-Carbazole-3-methanamine hydrochloride
PhiKan-083 hydrochloride
PK083 hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H18N2 · HCl |
| Molecular weight | 274.79 |
| MDL number | MFCD07168924 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | PhiKan083 is a small molecule that binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CNCC1=CC2=C(C=C1)N(CC)C3=C2C=CC=C3.[H]Cl |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
