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海葱次苷

Proscillaridin A
产品编号:4086344
规格:≥90% (HPLC)
CAS NO:466-06-8
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40863445 MG1390
408634425 MG5320
产品别名

466-06-8

海葱次苷

Proscillaridin A

Scillarenin 3β-rhamnoside

(3β)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide

3-(6-Deoxy-α-L-mannopyranosyloxyl)-14-hydroxybufa-4,20,22-trienolide

海葱苷 3β-鼠李糖甙

海葱次苷

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C30H42O8
Molecular weight
530.65
MDL number
MFCD00214065
Biochem/physiol Actions【生化/生理作用】
Proscillaridin A, a cardiac glycoside, is an antiarrhythmic drug that enhances DNMT inhibitors and HDAC inhibitors activity. Combination of decitabine with proscillaridin A produced profound gene expression reprogramming associated with down-regulation of 153 epigenetic regulators including SYMD3 and KDM8. Proscillaridin A was recently identified as a potent anti-HBV agent (IC50 = 7.2?nM).
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥90% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 2 mg/mL, clear
storage temp.【储存温度】
−20℃
SMILES string
C[C@]12CC[C@]3([H])[C@@]4(C)CC[C@H](O[C@]5([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C=C4CC[C@@]3([H])[C@@]1(O)CC[C@@H]2C6=COC(C=C6)=O
InChI
1S/C30H42O8/c1-16-24(32)25(33)26(34)27(37-16)38-19-8-11-28(2)18(14-19)5-6-22-21(28)9-12-29(3)20(10-13-30(22,29)35)17-4-7-23(31)36-15-17/h4,7,14-16,19-22,24-27,32-35H,5-6,8-13H2,1-3H3/t16-,19?,20?,21?,22?,24-,25+,26+,27-,28?,29?,30?/m0/s1
InChI key
MYEJFUXQJGHEQK-RLQJMXQZSA-N
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H301
Precautionary Statements
P301 + P310 + P330
Hazard Classifications【危险分类】
Acute Tox. 3 Oral
Storage Class Code【储存分类代码】
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
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