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SK33
产品别名
1928724-23-5
SK33
3-[3,5-Bis(trifluoromethyl)phenoxy]-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H13F9N2O3 |
| Molecular weight | 500.31 |
| Biochem/physiol Actions【生化/生理作用】 | SK33, a trifluoromethylated enobosarm analog, is a cell and brain penetrant, tissue selective and highly potent anti-androgen that reduces androgen receptor (AR) transcriptional activity. SK33 induces cell cycle arrest at G1 phase. It exhibits increased efficacy against acquired anti-androgen resistance prostate cancer cells. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC(C(NC1=CC(C(F)(F)F)=C(C#N)C=C1)=O)(C)COC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2 |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
